Clinical trials play an important role in improving cancer prevention, diagnosis and treatment. For some patients, taking part may offer access to new therapies that are not yet widely available. Your care team can help determine whether a clinical trial may be an option and explain what participation involves.
What is Endometrial Cancer ?
Endometrial cancer develops when cells in the lining of the uterus, called the endometrium, begin to grow and divide abnormally, sometimes forming a tumor. It is the most common type of uterine cancer.
Endometrial cancer is most often diagnosed after menopause, though it can occur earlier in people with certain hormone patterns or risk factors. If you or someone you care about has concerns, LifeBridge Health’s cancer specialists are here for the whole experience—supporting your body, well-being and peace of mind as you move through diagnosis and treatment.
Endometrial Cancer Symptoms
Symptoms of endometrial cancer often appear early, which can help with timely diagnosis. Signs may include:
- Longer or heavier menstrual periods
- Vaginal bleeding between periods or after menopause
- Watery or unusual vaginal discharge
- Pelvic pain or pressure
- Changes in urination or bowel habits
- Unexplained weight loss or fatigue
How Endometrial Cancer is Diagnosed
Evaluation for endometrial cancer usually begins when abnormal bleeding or other symptoms raise concern. Your care team can use several tests to confirm a diagnosis and plan treatment tailored to your unique case.
Pelvic Exam
Your provider examines the uterus, cervix and surrounding tissues to check for changes that may need further testing.
Transvaginal Ultrasound
A small ultrasound device is inserted into the vagina to take images of the uterus. This test often helps determine whether a biopsy is needed.
Endometrial Biopsy
A thin tube collects a small sample of the uterine lining. A pathologist examines the tissue under a microscope to check for cancer or precancerous changes.
Hysteroscopy or Dilation and Curettage (D&C)
If more information is needed, your doctor may recommend a more complex procedure to look inside the uterus and collect additional tissue.
Imaging Tests
CT, MRI or PET scans may be used to see whether the cancer has spread beyond the uterus.
Endometrial Cancer Treatment Options
Treatment decisions for endometrial cancer depend on the stage and type of cancer, hormone factors and your overall health. But care planning goes beyond test results. At LifeBridge Health, teams also consider the emotional impact of treatment and how care may affect your body, daily life and future plans, including family planning.
Our specialists work together to help you understand your options and make decisions that reflect your needs and priorities.
Surgery
Surgery is the main treatment for most people with endometrial cancer. This usually involves removing the uterus (hysterectomy). In some cases, the ovaries, fallopian tubes and nearby lymph nodes may also be removed.
Radiation Therapy
Radiation therapy uses high-energy beams to target and destroy cancer cells. It may be used alone or combined with other treatments, depending on your needs.
Chemotherapy
Chemotherapy uses medication to kill cancer cells or slow their growth. It may be recommended in advanced cases.
Hormone Therapy
Some endometrial cancers respond to treatments that block or lower hormone levels. This option may be considered in select cases, including for people who wish to preserve fertility.
Immunotherapy
Immunotherapy uses medication to help the immune system recognize and attack cancer cells.
Targeted Therapy
Targeted therapy focuses on specific parts of cancer cells that help them grow. This approach helps limit damage to healthy tissue.
Clinical Trials
Supportive Services
When you receive cancer care at LifeBridge Health, you have access to supportive services like counseling, integrative therapies and support groups. These resources are designed to help patients care for their physical and emotional well‑being throughout treatment and beyond.