Active Trial Listings - The Rubin Institute for Advanced Orthopedics

RIAO Publications

Degenerative Joint Disease

Long-Term Safety Follow-Up of Study Subjects Who Were Previously Enrolled in a Tissue Gene Clinical Trial and Were Administered TissueGene-C.
PI: Ronald E. Delanois, M.D.

Diabetic Foot Ulcers

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Study to Evaluate the Efficacy and Safety of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects Who Have Diabetic Foot Ulcer (DFU) With and Without Peripheral Arterial Disease (PAD).
PI: Noman Siddiqui, D.P.M.

Clinical Outcomes for Diabetic Foot Ulcers Treated with Clostridial Collagenase (SANTYL®) Ointment or with a Comparator Product Containing Silver.
PI: Noman Siddiqui, D.P.M.

Diabetic Foot Ulcers/Venous Leg Ulcers

A Prospective, Randomized, Comparative Effectiveness Study of a Single-Use, Negative Pressure Wound Therapy System (PICO) versus a Traditional Negative Pressure Wound Therapy System (tNPWT) in the Treatment of Lower Extremity Ulcers
PI: Noman Siddiqui, D.P.M.

A Phase 3 Randomized, Placebo-controlled, Blinded Study to Investigate the Safety and Efficacy of a Topical Gentamicin-Collagen Sponge in Combination with systemic Antibiotic Therapy in Diabetic Patients with an Infected Foot Ulcer.

Infected Fractures

A Phase 2a Randomized, Single-Blind, Placebo-Controlled, 24-week Escalating Dose Study to Assess the Safety, Tolerability and Clinical Activity of 3 Concentrations of Locally Applied MBN-101 to Infected Osteosynthesis Sites.
PI: Janet D. Conway, M.D.

Limb Lengthening

Clinical Evaluation of the Ellipse Intramedullary Limb Lengthening System (IMLL).
PI: John E. Herzenberg, M.D.


SHB-OCSI002: Prospective, Randomized Trial of a Novel Brace Technology for the Non-Operative Treatment of Knee Osteoarthritis.

A Prospective, Randomized, Double-Blind, Placebo Controlled Feasibility Study to Evaluate Efficacy and Safety of an Active Pulsed Electromagnetic Field for the Treatment of Osteoarthritis of the Knee
PI: Ronald E. Delanois, M.D.

Total Knee Arthroplasty

A Multi-institutional Prospective Randomized Trial to Evaluate the Canady Hybrid Plasma Scalpel in Patients Undergoing Primary Total Knee Arthroplasty

Wound Healing

Impact of V.A.C. Veraflo™ Therapy In Wounds Requiring Debridement Within An Orthopedic Practice
PI: Janet D. Conway, M.D.

Effectiveness of CelluTome Epidermal Harvesting System in Autologous Skin Grafting of Chronic Wound Patients
PI: Noman A. Siddiqui, D.P.M.